Protein-based drugs are used in the treatment of every kind of malady, from cancer to heart disease to rheumatoid arthritis. But the proteins are almost always modified with chemical appendages that help them navigate through the body or target specific tissues. A new study reveals an efficient means of attaching lipids (fat molecules) to peptides (the building blocks of proteins). This can improve the molecules’ drug-delivery capabilities.
The new findings are reported in the Proceedings of the National Academy of Sciences.