Remarkably resistant to mechanical deformations, collagen forms the structural scaffold of connective tissues in humans. One of the most interesting characteristics of collagen fibers is their enormous tensile strength. Combining the advantages of both polarimetry and Infrared (IR) microscopy, IR polarimetric spectroscopic imaging is a unique approach that provides the architectural fine structure of bio-molecules such as collagen. A chemical image of pre-cancerous breast tissue is colorized here based on collagen fibrillar content, allowing researchers to study the impact of collagen orientation on the disease progression using only light and computational methods. Designing and implementing microscopes that enable such analytical measurements in IR is the focus of my research. It paves the way for a fast contrast-enhanced imaging platform for collagen scaffolds, which you might even say is the future of tissue engineering.