A postdoctoral research associate position is available to work on an NIH-funded project in the lab of Prof. Andrew Gulick within the Department of Structural Biology, University at Buffalo. The Gulick Lab investigates the structural enzymology of proteins involved in the biosynthesis of bacterial natural products. Through combinations of structural biology, biochemical characterization, protein engineering, and biocatalysis, we aim to explore the ability of bacteria to produce diverse small molecules to help them adapt to the challenges of surviving in diverse environments.
The postdoctoral associate will be responsible for:
- protein production, purification, and analysis, including development and implementation of biochemical assays
- informatic and genome mining to identify, characterize, and understand the diverse biosynthetic pathways of bacterial sources
- protein structure determination through X-ray crystallography and/or cryo-electron microscopy and single particle analysis
- data analysis, maintenance, and interpretation, including contributions on authoring publications and dissemination of research
Minimum Qualifications
- PhD in Biochemistry, Chemistry, or related field
- Background in protein biochemistry, enzymology, biophysical analysis, or structural biology
- Ability to analyze, publish, and present research data
- Self-motivation, ability to work both independently and collaboratively as a team. Ability to manage time and organization on multiple projects
Preferred Qualifications
- Interest in natural product biosynthesis, including pathway reconstitution, genetic manipulation, small molecule isolation and characterization
- Expertise in enzymology, including assay development, LC-MS and HPLC analysis
- Experience with X-ray crystallographic analysis and protein structure determination or single particle cryo-electron microscopy structure determination and analysis
- Familiarity with computation tools for protein structure determination and analysis.
Applicants will be required to apply formally through the UB Jobs website, which will be posted shortly (a link will be added to my homepage). In the interim, interested candidates should send the following to amgulick@buffalo.edu
- Cover Letter describing current research experience, future professional goals, and how your experience fits with the broad goals of our lab
- Curriculum vitae
- Names of three references. Letters of support will be solicited from selected candidates.
Applications will be reviewed starting Oct 31 and will continue until filled.
As an Equal Opportunity / Affirmative Action employer, the UB Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, sexual orientation, gender identity, national origin, and veteran or disability status.