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  • Atomic structure of antifungal drug opens door to less-toxic derivatives

    Dec 9, 2021 1:15 pm by Liz Ahlberg TouchstoneResearch
    Illinois chemistry professor Martin Burke co-led a team that mapped the unusual aggregate structure of the antifungal drug amphotericin B, illuminating the path to develop less-toxic forms of the drug. Photo by L. Brian Stauffer

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    • Illinois chemistry professor Martin Burke co-led a team that mapped the unusual aggregate structure of the antifungal drug amphotericin B, illuminating the path to develop less-toxic forms of the drug. Photo by L. Brian Stauffer

    Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years.