Why is the use of hypersonic missiles in the Russia-Ukraine conflict significant? Mar 22, 2022 8:45 am by Lois YoksoulianExpert Viewpoints Share on Facebook Tweet Email Images Russia used a hypersonic ballistic missile to destroy an underground arms depot in western Ukraine, marking the first known use of a hypersonic missile in combat. Professor Kelly Stephani explains what makes hypersonic missiles different. Share on Facebook Tweet Email