Illinois Featured Content

  • Gene editing tool reduces Alzheimer’s plaque precursor in mice

    Dec 23, 2024 1:30 pm by Liz Ahlberg TouchstoneResearch
    Professor Pablo Perez-Pinera, center, with graduate students Shraddha Shirguppe, left, and Angelo Miskalis, led a team that applied the tool to reduce proteins associated with Alzheimer’s disease in mice. Photo by Fred Zwicky

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    • Professor Pablo Perez-Pinera, center, with graduate students Shraddha Shirguppe, left, and Angelo Miskalis, led a team that applied the tool to reduce proteins associated with Alzheimer’s disease in mice. Photo by Fred Zwicky

    A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer’s disease.