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  • Self-driving lab: AI and automated biology combine to improve enzymes

    Jul 1, 2025 2:45 pm by Liz Ahlberg TouchstoneInnovation
    With AI to guide enzyme improvement and automated synthetic biology to rapidly make and test new variants, Illinois researchers developed a user-friendly system to drastically improve enzyme performance. Pictured, from left: Nilmani Singh, Jingxia Lu, Stephen Lane and Professor Huimin Zhao with the BioAutomata, an AI-driven robotic biomanufacturing platform. Photo by Craig Pessman

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    By combining artificial intelligence with automated robotics and synthetic biology, U. of I. researchers have dramatically improved performance of two important industrial enzymes — and created a user-friendly, fast process to improve many more.

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