The Center for Advanced Electronics through Machine Learning (CAEML), which has been funded as a Phase I IUCRC by the National Science Foundation since 2017, has just received funding from NSF to proceed with a second five-year phase. Phase II research will officially kick off on August 1, 2022. AEML’s research vision is to apply machine learning to the design of optimized microelectronic circuits and systems, thereby increasing the efficiency of electronic design automation (EDA) and resulting in reduced design cycle time and radically improved reliability.