Lurking in more than 99% of soybean fields across the Midwest is a worm capable of feeding on and damaging entire crops. Millions of dollars have been spent trying to combat these destructive pests through the development of resistant soybean plants, but after decades of successful use, those solutions have begun to fail. Once again, soybean production is in trouble, and Illinois ECE researchers are being forced back to the drawing board, but this time they are looking to attack the nematode from within.