"In this study, we developed an integrated computational framework for the analysis and exploitation of the solvent metabolism by C. acetobutylicum," said Chen Liao, a bioengineering graduate student and first author of the paper, "Integrated, Systems Metabolic Picture of Acetone-Butanol-Ethanol Fermentation by Clostridium acetobutylicum," appearing in this week’s Early Edition of Proceedings of the National Academy of Sciences of the United States of America.