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  • PFAS exposure, high-fat diet drive prostate cells’ metabolism into pro-cancer state

    The research team led by Zeynep Madak-Erdogan, with Michael J. Spinella and Joseph Irudayaraj

    A new study in mice suggests that consuming a high-fat diet in combination with exposure to PFAS triggers changes in benign and malignant prostate cells that promote rapid tumor growth. Food science and human nutrition professor Zeynep Madak-Erdogan, center, led the study. Co-authors include comparative biosciences professor Michael J. Spinella, left, and bioengineering professor Joseph Irudayaraj.

    Photo by L. Brian Stauffer


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  • Editor’s Note: To reach Zeynep Madak-Erdogan, call 217-300-9063; email

    To reach Michael J. Spinella, email

    To reach Joseph Irudayaraj, email

    The paper “Per- and polyfluoroalkyl substance exposure combined with high-fat diet supports prostate cancer progression” is available online or from the News Bureau.

    DOI: 10.3390/nu13113902