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  • A heart of stone: Study defines the process of and defenses against cardiac valve calcification

    Two men in front of projected microscope images.

    University of Illinois Urbana-Champaign professor Bruce Fouke, right, and researcher Miyandi Sivaguru led a study that detailed the process of calcification in the heart’s aortic valve and the body’s defense tactics that can slow the process.

    Photo by Fred Zwicky


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  • Editor’s note:   

    To reach Bruce Fouke, email To reach Mayandi Sivaguru, email  

    The paper, “Osteopontin stabilization and collagen containment slows amorphous calcium phosphate transformation during human aortic valve leaflet calcification,” is available online.

    DOI: 10.1038/s41598-024-62962-8