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  • Gene expression altered by direction of forces acting on cell

    Professor Ning Wang sits in his lab.

    Forces applied across the width of a cell pull at the support fibers like violin stings being plucked, Illinois engineering professor Ning Wang said. The fibers stretch the chromosomes in the cell and increase gene expression.

    Photo by L. Brian Stauffer

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  • Editor’s notes: To reach Ning Wang, call 217-265-0913; email nwangrw@illinois.edu. 

    The paper “Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells” is available online.

    DOI: 10.1038/s41467-020-18584-5