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  • Experts boost activity of potential therapeutic target in triple-negative breast cancer

    The researchers in the laboratory.

    John Katzenellenbogen, left, Benita Katzenellenbogen and their colleagues found that stimulating estrogen receptor beta in triple-negative breast cancers alters the activity of cancer-related genes and reduces the growth and metastasis of these breast cancers. The work was conducted in human TNBC cells and in mice with TNBC tumors expressing varying levels of ER beta.

     

    Photo by Fred Zwicky

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  • Editor’s notes

    To reach Benita Katzenellenbogen, email katzenel@illinois.edu.

    To reach John Katzenellenbogen, email jkatzene@illinois.edu.

    The paper “Estrogen receptor beta 1: A potential therapeutic target for female triple-negative breast cancer”  is available online and from the U. of I. News Bureau.

    DOI: 10.1210/endocr/bqac172